Analyzing Acts 16:6-10 (ESV)
Acts 16:6 (ESV): "And they went through the region of Phrygia and Galatia, having been forbidden by the Holy Spirit to speak the word in Asia."
Acts 16:7 (ESV): "And when they had come up to Mysia, they attempted to go into Bithynia, but the Spirit of Jesus did not allow them."
Acts 16:9-10 (ESV): "And a vision appeared to Paul in the night: a man of Macedonia was standing there, urging him and saying, “Come over to Macedonia and help us.” And when Paul had seen the vision, immediately we sought to go on into Macedonia, concluding that God had called us to preach the gospel to them."
Note: "Asia" here refers to the Roman province in western Asia Minor (modern Turkey), not the continent.
The map illustrates the direct route Paul intended (Asia/Bithynia) and the critical pivot to Macedonia (Europe) that the Spirit commanded.
Paul's logical direction was west, towards the major metropolitan and commercial hubs of the Roman province of Asia, like Ephesus and Smyrna. However, the Holy Spirit intervened.
The call to Macedonia represented the most significant geographical pivot in the early Church—the crossing from the Asian continent to Europe. This decision fundamentally shaped the future of Western civilization.
The ultimate destination of Troas, and the subsequent sailing to Macedonia, placed Paul directly onto the Empire's communication superhighway.